Thursday, August 25, 2011

Question on Acidic Strength

Out of the following two compounds (1) and (2) respectively, which one has the most acidic alpha-hydrogen and why?




Answer:


The second one will be more stable, because after the removal of the alpha-hydrogen, the five membered ring becomes aromatic and hence becomes more stable. So, (2) has the most acidic alpha-hydrogen compared to that of (1).


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